Zhang et al. (2016) PNAS. First author Dr. Jiwei Zhang (Schilling Lab). Whole shotgun transcriptomics in a space-for-time wood wafer set-up with brown rot fungi - there is an oxidative plot twist in the first 48 hours when these fungi invade wood.
Song et al. (online first) Functional Ecology. First author Dr. Zewei Song (Schilling Lab, now in Plant Pathology at UofM). Peter Kennedy onboard to help deploy FunGuild - read this tale of a struggle for decay dominance that all started in healthy trees.
Presley et al. (online first) Fungal Genetics & Biology. First author Gerry Presley (PhD candidate, Schilling Lab). A genomics-informed revisit of oxalate dynamics during brown rot - more traction with the wood wafer 'chop chop.'
About the Lab
Since 2006, our research has been basic and applied mycology. We focus most of our efforts on fungi that decompose non-edible plant tissues like wood, with specific attention to the basics of how they metabolically transform carbon. Understanding that underlying biology is very important when prospecting new metabolites and pathways for biomass conversion and medicine. It also provides biological insight into terrestrial carbon dynamics. Carbon cycling shapes our climate. The more we know about plant decomposition, the better we will be at predicting how our climate will change – plants are the largest pool of biotic carbon on Earth.
The techniques we use in the laboratory combine old and new, and are increasingly in a collaborative context. Wood-degradation research has been active for over 100 years, often with the focus on durability. Many techniques evolved in a pre-molecular era and focused as much on analyzing the changes in the plant tissues (lignocellulose) as they did on the fungi. These were often quite clever and a product of painstaking benchwork. With the proliferation of DNA- and RNA-based tools, we now have an amazing window into the fungal processes and community assembly dynamics driving these processes. This adds to the picture rather than supplanting the old view; therefore, we are coupling modern tools (transcriptomics, proteomics, enzymatic assays) with traditional techniques, with the goal of linking fungi and their genomes to their functional roles.